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Table 1 Patient characteristics and ME status

From: Prospective evaluation of microscopic extension using whole-mount preparation in patients with hepatocellular carcinoma: Definition of clinical target volume for radiotherapy

 

Patients

ME positive

 

Characteristic

No (%)

%

P value

Age (y)

  

NS

   ≤60

39 (51.3)

87.2

 

   >60

37 (48.7)

73.0

 

Sex

  

NS

   Male

60 (78.9)

78.3

 

   Female

16 (21.1)

87.5

 

Status of Hepatitis

   

   HBsAg positive

62 (81.6)

85.5

NS

   HCVAb positive

3 (3.9)

33.3

 

   Others

11 (14.5)

63.6

 

AFP level (ng/ml)

  

<0.01

   Normal

43 (56.6)

69.8

 

   Elevated

33 (43.4)

93.9

 

Tumor size (cm)

  

NS

   ≤5

41 (53.9)

78.0

 

   >5

35 (46.1)

82.9

 

TNM stage

  

NS

   I

42 (55.3)

83.3

 

   II

34 (44.7)

76.5

 

Platelets (G/L)

  

NS

   <100

11 (14.5)

81.8

 

   ≥100

65 (85.5)

80.0

 

AST level (U/L)

  

NS

   ≤40

54 (71.1)

85.2

 

   >40

22 (28.9)

68.2

 

ALT level (U/L)

  

NS

   ≤40

49 (71.1)

81.6

 

   >40

27 (28.9)

77.8

 

GGT level (U/L)

  

NS

   ≤55

43 (56.6)

81.4

 

   >55

33 (43.4)

78.8

 

Albumin level(g/L)

  

NS

   ≤35

8 (10.5)

75.0

 

   >35

68 (89.5)

80.9

 

BIL (μmol/L)

  

NS

   ≤17.1

59 (77.6)

78.0

 

   >17.1

17 (22.4)

88.2

 

PT(s)

  

NS

   ≤13.3

55 (72.4)

83.6

 

   >13.3

21 (27.6)

71.4

 

Tumor grade

  

<0.01

   1

6 (7.9)

16.7

 

   2

43 (56.6)

79.1

 

   3

27 (35.5)

96.3

 

All patients

76 (100)

80.3

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  1. Abbreviations: HBsAg = hepatitis B surface antigen; HCV Ab = hepatitis C virus antibody; AFP = serum α-fetoprotein; AST = serum aspartate aminotransferase level; ALT = serum alanine aminotransferase level; GGT = serum γ-glutamyltransferase; BIL = serum total bilirubin level; PT = prothrombin time; NS = not significant.