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Table 1 Patient characteristics

From: The effect of external beam radiotherapy volume on locoregional control in patients with locoregionally advanced or recurrent nonanaplastic thyroid cancer

Patient Characteristics

 

Distribution, n (%)

Gender

Female

19 (83)

 

Male

4 (17)

Age (years)

Median (range)

64 (37-76)

 

< 45

2 (8)

 

45 - 64

10 (44)

 

≥ 65

11 (48)

KPS

90

10 (43)

 

80

13 (57)

Histologic type

Papillary

19 (83)

 

Poorly differentiated

4 (17)

Recurrence

Primary tumor

8 (35)

 

Recurrent tumor

15 (65)

T stage at initial diagnosis

T1-2

1 (4)

 

T3

14 (61)

 

T4

8 (35)

N stage at initial diagnosis

N0

4 (17)

 

N1a

10 (44)

 

N1b

9 (39)

AJCC Stage at initial diagnosis

I-II

3 (12)

 

III

10 (44)

 

IVA

10 (44)

T stage at pre-EBRT

T0-2

3 (13)

 

T3

3 (13)

 

T4

17 (74)

N stage at pre-EBRT

N0

3 (13)

 

N1a

4 (17)

 

N1b

16 (70)

AJCC Stage at pre-EBRT

I-III

3 (13)

 

IVA

14 (61)

 

IVB

1 (4)

 

IVC

5 (22)

Tg* level(ng/mL)

Median (range)

10 (0.2-1411)

 

< 10

11 (48)

 

≥ 10

12 (52)

Thyroid surgery

Subtotal thyroidectomy

4 (17)

 

Total thyroidectomy

19 (83)

Lymph node surgery

CND

6 (26)

 

CND+Unilateral SND/MRND

14 (61)

 

CND+Bilateral SND/MRND

3 (13)

Postoperative residuum

No

3 (13)

 

Microscopic

2 (9)

 

Macroscopic

18 (78)

Radioiodine treatment

No

4 (17)

 

Yes

19 (83)

EBRT volume

Limited field

11 (48)

 

Elective field

12 (52)

EBRT dose (EQD2, Gy)

Median (range)

62.5 (60-69)

  1. Abbreviation: KPS = Karnofsky performance status; AJCC, American Joint Committee on Cancer; EBRT, external beam radiotherapy; Tg* = pre-EBRT serum thyroglobulin; CND = central compartmental neck dissection; SND = selective neck dissection; MRND = modified radical neck dissection; EQD2, biologically equivalent dose in 2 Gy fractions using a linear quadratic model (α/β ratio for acute effects on normal tissues and tumors = 10).