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Table 3 Dosimetric statistics for the specified OARs

From: Helical tomotherapy for single and multiple liver tumours

Structure

Parameter

HT

SaS-IMRT

p

Group 1 -single tumour group

Normal liver

Mean (Gy)

18.24 ± 6.73(10.84-31.09)

20.01 ± 7.86 (8.37-31.20)

n/a

 

V50%(%)

19.17 ± 5.62(10.83-22.50)

22.19 ± 7.13(14.17-31.25)

n/a

 

EUD

23.68 ± 5.14(16.60-33.97)

29.11 ± 5.46(21.52-37.14)

< 0.05

 

NTCP

1.69 ± 4.30(0.003-12.33)

6.80 ± 9.86(0.06-29.07)

0.051

Whole liver

V30 Gy(%)

36.41 ± 14.88(16.45-62.00)

39.44 ± 16.57(16.94-62.06)

n/a

Lt kidney

Mean (Gy)

2.48 ± 2.43 (0.30-6.44)

2.83 ± 3.61(0.17-9.00)

n/a

Rt kidney

Mean (Gy)

4.13 ± 3.09 (0.42-8.03)

5.55 ± 4.55(0.15-10.57)

n/a

GIS

Max (Gy)

30.18 ± 18.17(8.65-52.56)

32.67 ± 17.27(11.77-53.45)

n/a

Spinal cord

Max (Gy)

15.30 ± 9.14(5.12-34.28)

22.05 ± 11.10(4.58-34.78)

n/a

Group 2 -multiple tumours group

Normal liver

Mean (Gy)

25.89 ± 3.43(18.89-28.45)

29.73 ± 6.71 (15.54-36.96)

< 0.05

 

V50%(%)

36.46 ± 4.92(29.17-41.67)

51.74 ± 11.46(37.5-69.17)

< 0.05

 

EUD

28.09 ± 3.23(21.95-31.87)

34.68 ± 3.80(27.77-38.43)

< 0.05

 

NTCP

2.38 ± 2.25(0.07-6.15)

20.27 ± 13.29(1.23-38.33)

< 0.05

Whole liver

V30 Gy(%)

43.91 ± 10.43(23.12-53.42)

55.00 ± 14.28(27.11-74.97)

< 0.05

Lt kidney

Mean (Gy)

4.18 ± 2.94 (0.66-9.21)

2.60 ± 2.03(0.37-6.97)

n/a

Rt kidney

Mean (Gy)

6.11 ± 4.16 (0.99-12.38)

6.45 ± 4.76(0.93-14.58)

n/a

GIS

Max (Gy)

39.59 ± 12.42(21.42-53.20)

42.05 ± 12.36(19.67-52.78)

n/a

Spinal cord

Max (Gy)

18.08 ± 5.38(10.58-28.19)

23.66 ± 8.65(8.96-32.20)

< 0.05

  1. Abbreviation: SaS-IMRT: Step-and-shoot intensity-modulated radiotherapy;; HT: helical tomotherapy; EUD: Equivalent uniform dose; NTCP: Normal tissue complication probability; GIS: Gastrointestinal system (including stomach and small bowels); Lt: left side; Rt: right side; n/a: not statistical significance; statistical significance (p < 0.05) is reported between couples from the paired Wilcoxon signed-rank test analysis.