Table 3 Relation between prescribed and planned dose when the 3D dose distribution is considered for plan evaluation and corresponding probability of tumour control.
| Â | Â | D/Gy prescr. | BED/Gy prescr. | D2Gy/Gy prescr. |
planned | P B /% prescr. |
planned |
|---|---|---|---|---|---|---|---|
CONVT | PTV1 | 64.8 | 62.2 | 58.0 | 57.2 ± 3.1 | 66.7 | 48.8 ± 21.6 |
|  | PTV2 | 54.0 | 63.7 | 53.1 | 56.5 ± 2.3 | 93.4 | 86.5 ± 7.3 |
|  | PTV3 | 45.0 | 53.1 | 44.3 | 52.7 ± 1.5 | 76.7 | 89.2 ± 3.4 |
|  | Total |  |  |  |  | 47.8 | 38.1 ± 17.6 |
IFP | PTV1 | 70.2 | 66.5 | 64.0 | 64.1 ± 1.0 | 89.4 | 87.6 ± 2.9 |
|  | PTV2 | 59.4 | 70.1 | 58.4 | 63.3 ± 1.6 | 98.3 | 98.7 ± 0.7 |
|  | PTV3 | 50.4 | 59.5 | 49.6 | 53.6 ± 1.1 | 88.9 | 92.2 ± 0.8 |
|  | Total |  |  |  |  | 78.1 | 79.7 ± 2.5 |
IMRT1 | PTV1 | 70.2 | 66.5 | 64.0 | 65.5 ± 0.9 | 89.4 | 91.7 ± 2.3 |
|  | PTV2 | 59.4 | 70.1 | 58.4 | 63.7 ± 1.3 | 98.3 | 99.2 ± 0.2 |
|  | PTV3 | 50.4 | 59.5 | 49.6 | 54.5 ± 1.2 | 88.9 | 93.8 ± 0.9 |
|  | Total |  |  |  |  | 78.1 | 85.3 ± 2.7 |
IMRT2 | PTV1 | 70.2 | 73.2 | 74.0 | 73.6 ± 1.4 | 99.0 | 98.6 ± 0.6 |
|  | PTV2 | 59.4 | 72.0 | 60.0 | 64.6 ± 1.3 | 98.8 | 99.4 ± 0.2 |
|  | PTV3 | 50.4 | 59.5 | 49.6 | 51.7 ± 0.7 | 88.9 | 91.2 ± 0.9 |
|  | Total |  |  |  |  | 87.0 | 89.4 ± 1.6 |
± SD/Gy
± SD/%- D is the prescribed dose by the radiation oncologist;
- BED is the biological effective dose corresponding to the prescribed dose D;
- D2Gy is the prescribed dose converted into a fractionation of 2 Gy;
is the mean dose planned in each region of interest for a fractionation of 2 Gy averaged for all patients;- SD is the standard deviation for all patients;
- PB is the expected tumour control probability for the prescribed dose D;
is the estimated average probability of tumour control for the planned dose distribution.