Accelerated partial breast irradiation using multicatheter brachytherapy for select early-stage breast cancer: local control and toxicity

Table 3 Comparison of dosimetric parameters according to the late treatment toxicity

Toxicity		No (%)	V₁₀₀ (cm³)	P ^‡	V₁₅₀ (cm³)	P ^‡	DHI	P ^‡
Skin
	Yes*	11 (22.9)	51.3 ± 12.1	0.221	25.7 ± 6.2	0.222	0.51 ± 0.03	0.105
	No	37 (77.1)	43.0 ± 18.9		22.0 ± 8.7		0.49 ± 0.03
Subcutaneous tissue
	Yes^†	26 (54.2)	50.2 ± 18.2	0.018	25.1 ± 8.1	0.034	0.50 ± 0.03	0.099
	No	22 (45.8)	37.5 ± 15.0		19.9 ± 7.8		0.48 ± 0.03
Fat necrosis
	Yes	5 (10.4)	40.4 ± 18.7	0.529	21.0 ± 9.8	0.560	0.48 ± 0.02	0.465
	No	43 (89.6)	45.4 ± 17.9		23.1 ± 8.1		0.49 ± 0.03

Abbreviation: V₁₀₀ and V₁₅₀= volumes receiving 100% and 150% of the prescribed dose; DHI = dose homogeneity index, (V₁₀₀ - V₁₅₀)/V₁₀₀.
*Grade 1 to 2 toxicity.
^†Grade 1 to 2 toxicity. Five patients with asymptomatic fat necrosis also had grade 2 subcutaneous toxicity.
^‡t-test.

ISSN: 1748-717X