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Table 5 Response dose and survival fraction (SF2) for different clinical stage of intra-hepatic tumor.

From: Biological impact of geometric uncertainties: what margin is needed for intra-hepatic tumors?

SF2for different clinical stage and pathology cell type (Liu, 2005)

  

Clinical stage

  

IIb

IIIb

IV

Pathology typing

   

Hepatocellular carcinoma

0.28

0.47

0.61

Bile duct epithelial carcinoma

0.41

0.57

0.78

Radiation dose needed for tumor response

  

response

non response

HCC without PVT (Park, 2002)

50.1 Gy

44.3 Gy

HCC with PVT (Kim, 2005)

BED 59.9 Gy

BED 55.2 Gy