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Table 1 Correlation between clinical and pathological factors before CRT and pathologica Response in rectal cancer patientsl

From: Circulating lymphocyte number has a positive association with tumor response in neoadjuvant chemoradiotherapy for advanced rectal cancer

 

Non-CR (63)

CR (10)

p value

Age (years)

63.4 ± 9.9

65.4 ± 11.2

0.455

Sex

   

Male

39

6

0.908

Female

24

4

 

T stage

   

2

12

1

0.901

3

45

8

 

4

6

1

 

N stage

   

0

49

9

0.487

1

14

1

 

Clinical stage

   

≤2

48

9

0.327

≥3

15

1

 

Histology

   

Differentiated

61

9

0.313

Undifferentiated

2

1

 

Size

   

≤40 mm

29

8

0.046*

>40 mm

34

2

 

Circumferential extent

   

≤60%

27

8

0.029*

>60%

36

2

 

Distance from anal verge

   

>5 cm

21

5

0.307

≤5 cm

42

5

 

Chemo regimen

   

UFT+LV

55

6

0.148

5Fu

4

2

 

S1

4

2

 

CEA

   

>5.0 ng/ml

35

3

0.120

≤5.0 ng/ml

27

7

 
  1. The size of the tumor was defined as the largest diameter determined by CT, and circumferential extent and distance from the anal verge were determined by colonoscopy
  2. performed before CRT
  3. *: p < 0.05