Quality of life and tumor control after short split-course chemoradiation for anal canal carcinoma

Radiation Oncology

Table 2 EORTC QLQ-C30

	CHUM N = 30 [Standard Deviation]	GUH[14] N = 41	BCCA[15]Patients N = 50	BCCA Volunteers N = 50	Zurich[16]EBRT N = 47	Zurich BT N = 34
Functional scales
Global quality of life	70 [± 25]	71 [± 21]	66 [± 28]	78 [± 20]	86 [± 22]	72 [± 23]
Physical function	87 [± 14]	79.5 [± 22]	74 [± 29]	89 [± 14]	78 [± 27]	76 [± 31]
Role function	77 [± 26]	85 [± 21]	76 [± 33]	87 [± 25]	77 [± 32]	66 [± 37]
Emotional function	77 [± 26]	77 [± 25]	74 [± 28]	81 [± 16]	80 [± 24]	77 [± 25]
Cognitive function	85 [± 25]	76 [± 23]	75 [± 24]	82 [± 20]	75 [± 34]	78 [± 36]
Social function	74 [± 34]	82 [± 28]	73 [± 35]	90 [± 20]	77 [± 32]	70 [± 36]
Symptoms scales
Fatigue	28 [± 29]	27 [± 22]	36 [± 30]	20 [± 21]	27 [± 9]	29 [± 11]
Pain	20 [± 25]	15 [± 21]	6 [± 17]	1 [± 14]	7 [± 2]	24 [± 15]
Nausea, vomiting	1 [± 4]	6 [± 15]	23 [± 15]	14 [± 22]	1 [± 0]	2 [± 0]
Single items
Dyspnea	18 [± 26]	13 [± 22]	23 [± 33]	8 [± 16]	16 [± 7]	18 [± 7]
Sleep disturbance	26 [± 31]	23.5 [± 29]	29 [± 32]	22 [± 28]	29 [± 15]	33 [± 16]
Appetite loss	10 [± 23]	10 [± 19]	13 [± 22]	3 [± 15]	8 [± 3]	8 [± 3]
Diarrhea	28 [± 40]	28 [± 36]	27 [± 32]	5 [± 12]	24 [± 9]	29 [± 9]
Constipation	7 [± 19]	15 [± 21]	24 [± 32]	8 [± 16]
Financial impact	20 [± 31]	15 [± 28]	23 [± 37]	8 [± 20	13 [± 6]	17 [± 10]

EORTC QLQ-C30 results of this study and of the literature. The questionnaire assesses cancer-specific QOL. For all the questions, a scale from 1 to 4 was used (1: not at all, 2: a little, 3: quite a bit, 4: very much). All scores were linearly transformed such that all scales range from 0 to 100. For the six functional items, the higher score represents a higher level of functioning and for the symptoms/single items, a higher score means a higher level of symptomatology/problems. Brackets indicate "standard deviation". N = number of patients.

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