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Table 6 Studies of hypopharyngeal cancer treated with IMRT.

From: Intensity modulated radiotherapy with concurrent chemotherapy for larynx preservation of advanced resectable hypopharyngeal cancer

Author (year)

Inclusion/Stage

Case no.

Follow-up (months)

Survival

Larynx Preservation

Lee et al. (2007) [14]

Retrospective review 2002-2005 Stage III-IV

11

24 (median)

53% (2-year OS)

53% (2-year LFS)

Studer et al. (2006) [15]

Retrospective review 2002-2005 T1-4N0-3

29

16 (mean)

90% (2-year DFS)

96% (LP)

this study (2010)

Retrospective review 2003-2007 T2-4aN0-2c

33

19 (median)

22 (mean)

55% (2-year OS)

44% (5-year OS)

51% (2-year DFS)

41% (5-year DFS)

54% (2-year LFS)

43% (5-year LFS)

49% (2-year FLPS)

40% (5-year FLPS)

  1. Abbreviation: IMRT, intensity modulated radiotherapy; OS, overall survival rate; DFS, disease-free survival rate; LFS: laryngectomy-free survival rate; LP: larynx preservation rate; FLPS: functional larynx-preservation survival rate