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Table 5 Treatment toxicities.

From: Intensity modulated radiotherapy with concurrent chemotherapy for larynx preservation of advanced resectable hypopharyngeal cancer

 

Patient number

 

Surgery

CCRT

p -value

Patients

14

33

 

Acute toxicities

   

   Skin (≥Gr. 2)

5

6

0.194

   Mucositis (≥Gr. 2)

1

13

0.027

   Pharyngitis (≥Gr. 2)

9

29

0.060

   Pharyngitis (≥Gr. 3)

0

10

0.020

   Leukopenia (≥Gr. 3)

0

5

0.123

   Anemia (≥Gr. 2)

1

11

0.060

   Weight loss (≥Gr. 2)

4

13

0.480

   Wound infection

3

1*

0.039

   Pharyngocutaneous fistula

3

1*

0.039

Late toxicities

   

   Xerostomia at 1 yr after treatment (≥Gr. 2)

1

0

0.121

   Neck fibrosis (≥Gr. 2)

3

3

0.246

   Feeding tube-dependent

0

1*

0.510

   Dysphagia (≥Gr. 2)

0

2

0.347

   Carotid artery blowout

0

1*

0.510

   Vocal cord palsy

 

4

 
  1. Abbreviation: CCRT, concurrent chemoradiotherapy
  2. *The patients underwent not only CCRT, but also salvage surgery.