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Table 4 Prognostic factors for overall survival in multivariate analysis.

From: Intensity modulated radiotherapy with concurrent chemotherapy for larynx preservation of advanced resectable hypopharyngeal cancer

Factors

5-year overall survival (all patients)

p-value

  

All patients

CCRT group

cT stage

 

0.671

0.376

   T1-3

67%

  

   T4a

16%

  

cTCI

 

0.815

0.621

   No

68%

  

   Yes

16%

  

cCCI

 

0.023

0.020

   No

57%

  

   Yes

0%

  

Performance

 

0.443

0.990

   ECOG 0

47%

  

   ECOG 1-2

0%

  

Treatment response

 

< 0.001

0.001

   CR

52%

  

   PR+SD+PD

NA*

  
  1. Abbreviation: CCRT, concurrent chemoradiotherapy; cTCI, clinical thyroid cartilage invasion; cCCI, clinical cricoid cartilage invasion; CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease; NA, not available
  2. *The longest follow-up of this subgroup is 28 months and 2-year survival rate is 15%.