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Table 3 Prognostic factors for overall survival in univariate analysis.

From: Intensity modulated radiotherapy with concurrent chemotherapy for larynx preservation of advanced resectable hypopharyngeal cancer

Factors

p-value

 

All patients

CCRT

Age ≥60 vs. <60 years

0.922

0.942

Histology Grade 1-2 vs. 3

0.995

0.768

Location Pyriform sinus vs. Pharyngeal wall vs. Post-cricoid

0.396

0.359

Stage II-III. vs. IVA

0.109

0.072

cT stage T1-3 vs. T4a

0.024

0.020

cTCI Yes vs. No

0.037

0.034

cCCI Yes vs. No

0.003

0.010

cN stage N0-2a vs. N2b-2c

0.087

0.051

Performance(ECOG) 0 vs. 1-2

0.025

0.037

Pretreatment hemoglobin ≤13 vs. >13 gm/dl

0.117

0.172

Treatment modality Surgery vs. CCRT

0.788

 

Total RT day (CCRT group) <60 vs. ≥60 days

 

0.568

Treatment response CR vs. PR+SD+PD

< 0.001

< 0.001

  1. Abbreviation: CCRT, concurrent chemoradiotherapy; cTCI, clinical thyroid cartilage invasion; cCCI, clinical cricoid cartilage invasion; CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease