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Table 1 Patient characteristics.

From: Intensity modulated radiotherapy with concurrent chemotherapy for larynx preservation of advanced resectable hypopharyngeal cancer

  

Treatment

 
  

Surgery

CCRT

p -value

  

No.(%)

No.(%)

 

No. of patients

 

14(30)

33(70)

 

Sex

male

13(93)

32(97)

0.523

 

female

1(7)

1(3)

 

Age(y)

≥ 60

7(50)

14(42)

0.633

 

< 60

7(50)

19(58)

 
 

Median

58

57

 
 

Range

43-73

40-71

 

Performance (ECOG)

0

10

23

0.805

 

1

4

9

 
 

2

0

1

 

Location

Pyriform sinus

11(79)

30(91)

0.085

 

Pharyngeal wall

0(0)

2(6)

 
 

Post-cricoid

3(21)

1(3)

 

Histology grade

1-2

8(57)

20(61)

0.292

 

3

6(43)

9(27)

 
 

NA

0(0)

4(12)

 

cT

1

0

1(3)

0.795

 

2

3(21)

7(21)

 
 

3

4(29)

6(18)

 
 

4a

7(50)

19(58)

 

cN

0

5(36)

9(27)

0.488

 

1

1(7)

7(21)

 
 

2a-2c

8(57)

17(52)

 

Clinical stage

II

2(14)

2(6)

0.652

 

III

2(14)

5(15)

 
 

IVA

10(71)

26(79)

 

cTCI

Yes

7(50)

19(58)

0.633

 

No

7(50)

14(42)

 

cCCI

Yes

2(14)

7(21)

0.581

 

No

12(86)

26(79)

 

RT dose(Gy)

Median

62

70

 
 

Range

60-70

70-75

 

Follow-up time(m)

Median

19.8

18.8

 
 

Range

6.7-67.9

1.9-72.3

 
  1. Abbreviation: CCRT, concurrent chemoradiotherapy; ECOG, Eastern Cooperative Oncology Group; NA, not available; cT, clinical T stage; cN, clinical N stage; cTCI, clinical thyroid cartilage invasion; cCCI, clinical cricoid cartilage invasion