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Table 1 Patient characteristics.

From: Chemo-radiation with or without mandatory split in anal carcinoma: experiences of two institutions and review of the literature

patient characteristics

Zurich

Montreal

P

 

(n = 32)

(n = 52)

 

Host factors

   

Age (years)

61 ± 13

56 ± 12

0.07

gender (% female)

69

62

 

Anatomical extent tumor size (%)

   

T1

13

15

 

T2

28

38

 

T3

38

21

 

T4

22

23

 

LN involvement (%)

  

0.08

N0

43

71

0.01

N1

17

8

 

N2

23

10

 

N3

17

12

 

Treatment-related factors

   

RT (Gy)

59.4 ± 1

52.1 ± 2

< 0.001

RT duration (days)

52 ± 8

50 ± 8

 

Split duration (days)

6 ± 8

14 ± 7

< 0.001

Inguinal RT (%)

56

98

<0.001

Chemotherapy (%)

81

100

<0.01

MMC (%)

78

98

<0.01

  1. Patient characteristics of patients treated with external beam radiotherapy at Zurich (n = 32) and Montreal (n = 52). MMC = Mitomycin-C, LN = lymph node, RT = radiotherapy.