Clonogenic survival of HDMEC after transfection with let-7g precursor or inhibitor. Cells were treated as described in 'Methods'. Bar charts: Left sided: Influence of the transfected molecules on clonogenic survival without RT. Negative controls were set 100%. Right sided: Survival of irradiated cells (2 Gy) after transfection with the miRNA precursor (pre-miR) or inhibitor (anti-miR). Only miR transfected samples without irradiation were set 100%. Bars: Mean (n = 3) with SD. *: P < 0.05 versus the pre-miR or anti-miR negative control.