Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 5 TCP-increase for different sensitivities of choline PET, low whole prostate dose, different α/β values, calculated α and high γ50 (ASTRO definition)

From: Choline PET based dose-painting in prostate cancer - Modelling of dose effects

α [Gy-1] α/β [Gy] γ50 Det. rate PET [%] Dose [Gy] SIB [Gy] Single dose [Gy] TCPconv [%] TCP Increase [%]
0.04 1.5 2.2 81 74 90 2 68.7 22.2
0.04 1.5 2.2 64 74 90 2 68.7 17.0
0.06 3.1 2.2 81 74 90 2 68.7 21.4
0.06 3.1 2.2 64 74 90 2 68.7 16.4
0.08 8.3 2.2 81 74 90 2 68.7 20.1
0.08 8.3 2.2 64 74 90 2 68.7 15.4
  1. Calculation of the TCP-increase after boosting choline PET positive regions within the prostate up to 90 Gy. α/β was set to either Fowler's/Wang's or Valdagni's value, α was analytically determined in order to achieve agreement between calculated TCD50 and TCD50 obtained by Cheung et al. γ50 was again taken from Cheung's data (ASTRO definition).