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Table 3 TCP-increase for low sensitivity of choline PET, high whole prostate dose, low γ50(CN + 2 definition) and Fowler's α/β

From: Choline PET based dose-painting in prostate cancer - Modelling of dose effects

α [Gy-1] α/β [Gy] γ50 Det. rate PET [%] Dose [Gy] SIB [Gy] Single dose [Gy] TCPconv [%] TCP Increase [%]
0.04 1.5 1.4 64 78 90 2 97.0 1.4
  1. Calculation of the TCP-increase after boosting choline PET positive regions within the prostate up to 90 Gy; the whole organ dose was set to 78 Gy. α/β is estimated from Fowler's data and γ50 from Cheung's data (CN + 2 definition). For choline PET a low sensitivity was used.