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Table 3 OARV Parameters

From: Intensity-modulated radiation therapy (IMRT) vs. 3D conformal radiotherapy (3DCRT) in locally advanced rectal cancer (LARC): dosimetric comparison and clinical implications

   D5 (Gy) V40 (cc)
   c3DCRT f3DCRT IMRT c3DCRT f3DCRT IMRT
BLADDER mean 48.8 48.4 46.2 94.7 60.9 34.4
  SD 0.5 0.5 4.1 66.2 26.5 24.9
  p p 1 < 0.05 p 2 = 0.06 Ref p 1 < 0.05 p 2 < 0.05 Ref
SMALL BOWEL mean 49.2 49.0 46.2 178.3 140.3 68.9
  SD 0.5 0.8 4.1 136.6 120.7 63.5
  p p 1 < 0.05 p 2 < 0.05 Ref p 1 < 0.05 p 2 < 0.05 Ref
RECTUM mean 50.7 50.8 50.6 162.3   157.7
  SD 0.6 0.6 2.3 55.7 56.5 54.8
  p p 1 = 0.8 p 2 = 0.7 Ref p 1 = 0.8 p 2 = 0.9 Ref
  1. OARV: Organs at risk volume
  2. c3DCRT: classic tridimensional conformal radiotherapy;
  3. f3DCRT: fitting tridimensional conformal radiotherapy,
  4. IMRT: intensity modulated radiation therapy;
  5. D5: minimal dose received by 5% of the OARV;
  6. V40: volume receiving ≥ 40 Gy
  7. GTV: gross tumor volume;
  8. PTV: planning target volume;
  9. p 1: c3DCRT vs IMRT;
  10. p 2: f3DCRT vs IMRT;
  11. Ref: Reference value