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Table 3 OARV Parameters

From: Intensity-modulated radiation therapy (IMRT) vs. 3D conformal radiotherapy (3DCRT) in locally advanced rectal cancer (LARC): dosimetric comparison and clinical implications

  

D5 (Gy)

V40 (cc)

  

c3DCRT

f3DCRT

IMRT

c3DCRT

f3DCRT

IMRT

BLADDER

mean

48.8

48.4

46.2

94.7

60.9

34.4

 

SD

0.5

0.5

4.1

66.2

26.5

24.9

 

p

p 1 < 0.05

p 2 = 0.06

Ref

p 1 < 0.05

p 2 < 0.05

Ref

SMALL BOWEL

mean

49.2

49.0

46.2

178.3

140.3

68.9

 

SD

0.5

0.8

4.1

136.6

120.7

63.5

 

p

p 1 < 0.05

p 2 < 0.05

Ref

p 1 < 0.05

p 2 < 0.05

Ref

RECTUM

mean

50.7

50.8

50.6

162.3

 

157.7

 

SD

0.6

0.6

2.3

55.7

56.5

54.8

 

p

p 1 = 0.8

p 2 = 0.7

Ref

p 1 = 0.8

p 2 = 0.9

Ref

  1. OARV: Organs at risk volume
  2. c3DCRT: classic tridimensional conformal radiotherapy;
  3. f3DCRT: fitting tridimensional conformal radiotherapy,
  4. IMRT: intensity modulated radiation therapy;
  5. D5: minimal dose received by 5% of the OARV;
  6. V40: volume receiving ≥ 40 Gy
  7. GTV: gross tumor volume;
  8. PTV: planning target volume;
  9. p 1: c3DCRT vs IMRT;
  10. p 2: f3DCRT vs IMRT;
  11. Ref: Reference value