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Table 1 Dosimetric summary of target volumes

From: Intensity-modulated radiation therapy (IMRT) vs. 3D conformal radiotherapy (3DCRT) in locally advanced rectal cancer (LARC): dosimetric comparison and clinical implications

   D95 (Gy) Dmin (Gy) Dmax(Gy)
   c3DCRT f3DCRT IMRT c3DCRT f3DCRT IMRT c3DCRT f3DCRT IMRT
GTV mean 47.5 47.5 46.9 46.7 46.6 45.1 50.2 50.3 51.6
  SD 0.6 0.7 2.3 0.4 0.6 2.0 1.0 1.0 2.7
  p p 1 < 0.05 p 2 < 0.05 Ref p 1 < 0.05 p 2 < 0.05 Ref p 1 =0.2 p 2 =0.3 Ref
PTV mean 47.1 46.9 45.7 39.5 42.2 39.2 51.1 51.2 54.0
  SD 0.5 0.5 0.8 4.2 1.2 1.7 0.6 0.5 2.6
  p p 1 < 0.05 p 2 < 0.05 Ref p1 = 0.4 p 2 < 0.05 Ref p 1 < 0.05 p 2 < 0.05 Ref
  1. c3DCRT: classic tridimensional conformal radiotherapy;
  2. f3DCRT: fitting tridimensional conformal radiotherapy,
  3. IMRT: intensity modulated radiation therapy;
  4. D95: minimal dose to 95% of the volume;
  5. GTV: gross tumor volume;
  6. PTV: planning target volume;
  7. SD: Standard deviation;
  8. p1: c3DCRT vs IMRT;
  9. p2: f3DCRT vs IMRT;
  10. Ref:Referencevalue