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Table 5 Maintenance sorafenib dose modification table

From: Maintenance of Sorafenib following combined therapy of three-dimensional conformal radiation therapy/intensity-modulated radiation therapy and transcatheter arterial chemoembolization in patients with locally advanced hepatocellular carcinoma: a phase I/II study

Dose level 1

Dose level 2

Dose level 3

400 mg b.i.d

400 mg q.d

400 mg q.o.d

200 mg × 2 tablets

b.i.d (morning & evening)

200 mg × 2 tablets

q.d (morning)

200 mg × 2 tablets

q.o.d (morning)