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Table 3 Differences between Nominal Index and Simple IMRT plans

From: Comparison of simple and complex liver intensity modulated radiotherapy

Structure

Index IMRT Mean [Range]

Simple IMRT Mean [Range]

p-value

Segment Number*

47 [34-52]

18 [6-30]

<0.001

Complexity Score

0.51 [0.2-0.72]

0.63 [0.35-0.85]

<0.001

RTOG CI

1.42 [0.99-2.02]

1.52 [1.11-2.21]

0.001

Monitor Units

1892 [953-3761]

1695 [934-3832]

0.012

PTV D95 (Gy)

42.4 [28.1-60.7]

42.4 [28.1-60.8]

0.197

PTV D99 (Gy)

41.0 [27.3-58.7]

40.6 [27.2-58.7]

<0.001

PTV Min. 0.5 mL (Gy)

40.0 [25.7-59.4]

39.5 [25.7-59.5]

0.006

PTV EUD (-20) (Gy)

44.5 [29.4-63.9]

44.6 [29.6-64.6]

0.066

Liver NTCP (%)

2.7 [0-5]

2.4 [0-5]

0.370

Effective Liver Volume

0.38 [0.07-0.7]

0.38 [0.07-0.71]

0.418

Mean Liver Dose (Gy)

15.1 [2.4-20.2]

15.1 [2.7-19.8]

0.809

Mean Kidney Dose (Gy)

3.3 [0-13.7]

3.4 [0.3-11.7]

0.509

Max. Cord Dose (Gy)

16.4 [2.6-24]

16.2 [2.3-24.8]

0.713

Max.Stomach Dose (Gy)

19.6 [1.1-30]

19.4 [0.6-30]

0.548

Max. Duodenum Dose (Gy)

10.1 [0-29.9]

9.9 [0-29.4]

0.648

Max. Bowel Dose (Gy)

9.9 [0-30]

9.7 [0-30]

0.545

Max. Esophagus Dose (Gy)

16.1 [0-30]

16.1 [0-29.6]

0.980

Max. Heart Dose (Gy)

24.5 [0-43.9]

25.3

0.048

Max. Ribs Dose (Gy)

37.7 [0-48]

38.2 [0-48]

0.044

Integral Dose (J)

68.7 [4.7-181.6]

69.1 [5.2-173.9]

0.374

  1. * primary endpoint for analysis
  2. Max. is maximum dose to 0.5 mL of relevant structure except for cord where the point maximum dose is reported.