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Table 1 Summary of DVH analysis for PTV_A, PTV_Pelvis and healhty tissue.

From: Whole abdomen radiation therapy in ovarian cancers: a comparison between fixed beam and volumetric arc based intensity modulation

  Objective IMRT6 IMRT15 RA15 RA6 p
     PTV_WAR (6524 ± 861 cm3)  
Mean [Gy] 25.0 Gy 26.8 ± 0.5 24.8 ± 0.9 25.5 ± 0.5 26.2 ± 0.7 a,c,d
EUD [Gy] - 25.9 ± 0.4 24.0 ± 1.0 25.0 ± 0.3 25.6 ± 0.7 a,c,d
D 2% [Gy] Minimise 35.1 ± 1.4 32.9 ± 2.7 31.5 ± 2.2 33.2 ± 2.6 a,b,c,d
U 5-95% Minimise 0.34 ± 0.05 0.32 ± 0.06 0.26 ± 0.04 0.30 ± 0.03 a,b,d
D 98% [Gy] > 22.5 Gy 22.3 ± 0.5 20.7 ± 1.4 21.9 ± 0.4 22.1 ± 0.9 a,c
V 90% [%] > 95% 99.0 ± 0.6 93.4 ± 7.3 98.6 ± 0.9 98.4 ± 1.7 a,b,c
V 95% [%] - 95.6 ± 1.6 89.5 ± 12.0 92.7 ± 2.4 94.1 ± 5.0 a,b,c,d
V 107% [%] Minimize 36.3 ± 7.7 13.7 ± 7.7 17.6 ± 8.2 20.1 ± 11.6 a,b,c,d
     PTV_Pelvis (1211 ± 158 cm3)  
Mean [Gy] 45.0 Gy 45.0 ± 0.0 45.0 ± 0.0 45.0 ± 0.0 45.0 ± 0.0 -
EUD [Gy] - 44.0 ± 1.6 44.0 ± 1.5 43.9 ± 1.6 44.0V1.9 NS
D 2% [Gy] < 47.3 Gy 47.6 ± 0.5 47.3 ± 0.4 47.5 ± 0.3 47.5 ± 0.2 NS
U 5-95% Minimise 0.1 ± 0.02 0.10 ± 0.01 0.10 ± 0.02 0.10 ± 0.02 NS
D 98% [Gy] > 40.5 Gy 42.2 ± 0.4 42.1 ± 0.5 41.7 ± 0.5 41.7 ± 0.2 NS
V 90% [%] > 95% 99.8 ± 0.2 99.7 ± 0.4 99.5 ± 0.3 99.5 ± 0.2 NS
V 95% [%] - 95.4 ± 1.9 95.2 ± 2.3 94.0 ± 2.1 94.2 ± 1.1 NS
V 107% [%] < 2% 0.7 ± 0.9 0.3 ± 0.6 0.5 ± 0.6 0.5 ± 0.6 NS
CI 95% minimise 1.60 ± 0.1 1.51 ± 0.1 1.50 ± 0.1 1.50 ± 0.1 NS
     Healthy tissue (25772 ± 7089 cm3)  
Mean [Gy] - 19.6 ± 2.1 17.6 ± 1.3 17.6 ± 1.5 18.6 ± 1.6 b,c
V 10 Gy [%] - 75.0 ± 6.7 71.1 ± 5.4 70.4 ± 5.1 72.8 ± 5.5 b,c
DoseInt [Gy cm 3 10 6 ] - 4.94 ± 0.90 4.48 ± 1.00 4.48 ± 0.92 4.74 ± 1.02 b.c
  1. Dx% = dose received by the x% of the volume; Vx% = volume receiving at least x% of the prescribed dose; CI = ratio between the patient volume receiving at least 95% of the prescribed dose and the volume of the total PTV. U5-95% = D5-D95/Dmean EUD = Equivalent Uniform Dose. DoseInt = Integral dose, [Gy cm3 106]. Statistical significance (p): a = IMRT15 vs RA15, b = IM6 vs RA6, c = IMRT15 vs IMRT6, d = RA15 vs RA6, NS = Not significative