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Table 1 Summary of DVH analysis for PTV_A, PTV_Pelvis and healhty tissue.

From: Whole abdomen radiation therapy in ovarian cancers: a comparison between fixed beam and volumetric arc based intensity modulation

 

Objective

IMRT6

IMRT15

RA15

RA6

p

    

PTV_WAR (6524 ± 861 cm3)

 

Mean [Gy]

25.0 Gy

26.8 ± 0.5

24.8 ± 0.9

25.5 ± 0.5

26.2 ± 0.7

a,c,d

EUD [Gy]

-

25.9 ± 0.4

24.0 ± 1.0

25.0 ± 0.3

25.6 ± 0.7

a,c,d

D 2% [Gy]

Minimise

35.1 ± 1.4

32.9 ± 2.7

31.5 ± 2.2

33.2 ± 2.6

a,b,c,d

U 5-95%

Minimise

0.34 ± 0.05

0.32 ± 0.06

0.26 ± 0.04

0.30 ± 0.03

a,b,d

D 98% [Gy]

> 22.5 Gy

22.3 ± 0.5

20.7 ± 1.4

21.9 ± 0.4

22.1 ± 0.9

a,c

V 90% [%]

> 95%

99.0 ± 0.6

93.4 ± 7.3

98.6 ± 0.9

98.4 ± 1.7

a,b,c

V 95% [%]

-

95.6 ± 1.6

89.5 ± 12.0

92.7 ± 2.4

94.1 ± 5.0

a,b,c,d

V 107% [%]

Minimize

36.3 ± 7.7

13.7 ± 7.7

17.6 ± 8.2

20.1 ± 11.6

a,b,c,d

    

PTV_Pelvis (1211 ± 158 cm3)

 

Mean [Gy]

45.0 Gy

45.0 ± 0.0

45.0 ± 0.0

45.0 ± 0.0

45.0 ± 0.0

-

EUD [Gy]

-

44.0 ± 1.6

44.0 ± 1.5

43.9 ± 1.6

44.0V1.9

NS

D 2% [Gy]

< 47.3 Gy

47.6 ± 0.5

47.3 ± 0.4

47.5 ± 0.3

47.5 ± 0.2

NS

U 5-95%

Minimise

0.1 ± 0.02

0.10 ± 0.01

0.10 ± 0.02

0.10 ± 0.02

NS

D 98% [Gy]

> 40.5 Gy

42.2 ± 0.4

42.1 ± 0.5

41.7 ± 0.5

41.7 ± 0.2

NS

V 90% [%]

> 95%

99.8 ± 0.2

99.7 ± 0.4

99.5 ± 0.3

99.5 ± 0.2

NS

V 95% [%]

-

95.4 ± 1.9

95.2 ± 2.3

94.0 ± 2.1

94.2 ± 1.1

NS

V 107% [%]

< 2%

0.7 ± 0.9

0.3 ± 0.6

0.5 ± 0.6

0.5 ± 0.6

NS

CI 95%

minimise

1.60 ± 0.1

1.51 ± 0.1

1.50 ± 0.1

1.50 ± 0.1

NS

    

Healthy tissue (25772 ± 7089 cm3)

 

Mean [Gy]

-

19.6 ± 2.1

17.6 ± 1.3

17.6 ± 1.5

18.6 ± 1.6

b,c

V 10 Gy [%]

-

75.0 ± 6.7

71.1 ± 5.4

70.4 ± 5.1

72.8 ± 5.5

b,c

DoseInt [Gy cm 3 10 6 ]

-

4.94 ± 0.90

4.48 ± 1.00

4.48 ± 0.92

4.74 ± 1.02

b.c

  1. Dx% = dose received by the x% of the volume; Vx% = volume receiving at least x% of the prescribed dose; CI = ratio between the patient volume receiving at least 95% of the prescribed dose and the volume of the total PTV. U5-95% = D5-D95/Dmean EUD = Equivalent Uniform Dose. DoseInt = Integral dose, [Gy cm3 106]. Statistical significance (p): a = IMRT15 vs RA15, b = IM6 vs RA6, c = IMRT15 vs IMRT6, d = RA15 vs RA6, NS = Not significative