Skip to main content

Table 2 Univariate and multivariate analyses for disease-free survival (DFS) with clinicopathological prognostic factors in patients with cervical cancer following radiotherapy

From: Carbonic anhydrase XII expression is associated with histologic grade of cervical cancer and superior radiotherapy outcome

 

Univariate

Multivariate

Clinicopathological factors

HR (95% CI)

p value*

HR (95% CI)

p value*

Age (> 40 years vs.≤ 40 years)

0.44(0.24-0.82)

0.01

0.46(0.23-0.93)

0.93

CA12 (Positive vs. Negative)

0.58(0.33-1.03))

0.06

0.54(0.28-1.05)

0.07

Histologic type (AD vs. SCC)

2.37(1.16-4.89)

0.02

2.14(0.88-5.20)

0.09

Tumor size (1 unit increase)

1.35(1.13-1.63)

< 0.01

1.11(0.88-1.40)

0.40

Histological grade (MD vs. WD)

2.14(0.83-5.48)

0.11

2.20(0.75-6.42)

0.15

Histological grade (PD vs. WD)

4.54(1.68-12.34)

< 0.01

3.52(1.14-10.86)

0.03

Nodal status (Positive vs. Negative)

3.13 (1.68-5.86)

< 0.01

2.17(1.09-4.34)

0.03

FIGO stage (IIIA-IVA vs. I~IIB)

2.96(1.52-5.75)

< 0.01

3.16(1.60-6.26)

< 0.01

FIGO stage (IVB vs. I~IIB)

8.23(3.96-17.07)

< 0.01

5.57(2.28-13.63)

< 0.01

  1. SCC: Squamous cell carcinoma; AD: Adenocarcinoma and Adenosquamous carcinoma; WD: well differentiated; MD: moderately differentiated; PD: poorly differentiated; HR: hazard ratio; CI: confidence interval
  2. * from the Cox regression analysis