Figure 8

Illustration of the consequences of an infiltrative growth pattern on deformable image registration: left image) infiltrative growth pattern of the NSCLC (yellow with mesh points on the surface); middle image) tumor regression (red with mesh points on the surface) with release of the pulmonary structures; right image) transformation of the middle image into the left image based on the mesh points on the surface of the GTV: note the distortion of the pulmonary structures.