Figure 5

Patient # 12: a) planning CT; b) follow-up CT at the end of treatment; c) difference image between planning CT and follow-up CT; d) deformed follow-up CT using all target and organs-at risk meshes; e) deformed follow-up CT using target, lung and spinal cord; f) difference image between planning CT and deformed follow-up CT based on all target organs-at risk meshes. The contours of the macroscopic primary tumor in the planning CT and the follow-up CT are shown in red. Note the distortion of the vertebral body and the aorta without using meshes of these organs for deformable registration in e).