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Table 3 Changes of mean TGF-β1 level during the course of radiation therapy

From: The TGF-β1 dynamics during radiation therapy and its correlation to symptomatic radiation pneumonitis in lung cancer patients

  

Mean ± SD (× 104 pg/ml)

 
 

Time

RP

Non-RP

p value*

RP1

Before RT

2.8 ± 0.8

2.3 ± 1.1

0.157

(n = 17)

Beginning of RT

2.4 ± 0.7

2.5 ± 1.1

0.738

 

Middle of RT

2.0 ± 0.6

2.4 ± 1.2

0.19

 

End of RT

2.1 ± 0.7

2.2 ± 0.9

0.879

 

2 wks after RT

2.1 ± 0.4

2.0 ± 0.8

0.806

 

4 wks after RT

2.8 ± 1.1

1.7 ± 0.5

0.007

RP2

Before RT

2.5 ± 1.0

2.6 ± 0.9

0.844

(n = 8)

Beginning of RT

1.9 ± 0.6

2.6 ± 0.9

0.079

 

Middle of RT

1.8 ± 0.7

2.3 ± 0.9

0.168

 

End of RT

1.9 ± 0.6

2.2 ± 0.8

0.352

 

2 wks after RT

2.1 ± 0.7

2.0 ± 0.9

0.787

 

4 wks after RT

3.3 ± 1.7

2.0 ± 0.9

0.062

  1. Abbreviations: RT, radiation therapy; wks, weeks; RP1, development of any grade of radiation pneumonitis; RP2, development of grade ≥ 2 radiation pneumonitis;
  2. * student's t-test
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Radiation Oncology

ISSN: 1748-717X

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