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Table 2 Dosimetric risk factors for development of RP ≥ grade 2

From: The TGF-β1 dynamics during radiation therapy and its correlation to symptomatic radiation pneumonitis in lung cancer patients

  

Mean ± SD

 
 

DVH parameters

RP

Non-RP

p value*

Whole lung

MLD (cGy)

1188 ± 354

957 ± 382

0.077

 

V5 (%)

58 ± 15

45 ± 12

0.035

 

V10 (%)

43 ± 13

34 ± 13

0.049

 

V20 (%)

29 ± 8

22 ± 11

0.049

 

V30 (%)

22 ± 7

17 ± 9

0.068

 

V40 (%)

15 ± 5

12 ± 7

0.299

Ipsilateral lung

MLD (cGy)

1986 ± 491

1512 ± 612

0.018

 

V5 (%)

78 ± 13

63 ± 17

0.003

 

V10 (%)

67 ± 11

52 ± 19

0.006

 

V20 (%)

49 ± 11

38 ± 17

0.032

 

V30 (%)

38 ± 11

29 ± 15

0.053

 

V40 (%)

24 ± 9

22 ± 14

0.655

  1. Abbreviations: RP, radiation pneumonitis; DVH, dose volume histogram; MLD, mean lung dose;
  2. V5, the percentage of the irradiated lung volume receiving a radiation dose exceeding 5 Gy;
  3. V10, the percentage of the irradiated lung volume receiving a radiation dose exceeding 10 Gy;
  4. V20, the percentage of the irradiated lung volume receiving a radiation dose exceeding 20 Gy;
  5. V30, the percentage of the irradiated lung volume receiving a radiation dose exceeding 30 Gy;
  6. V40, the percentage of the irradiated lung volume receiving a radiation dose exceeding 40 Gy
  7. * student's t-test
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Radiation Oncology

ISSN: 1748-717X

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