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Table 1 Inhibitors of ATM and/or ATR

From: The ATM and ATR inhibitors CGK733 and caffeine suppress cyclin D1 levels and inhibit cell proliferation

Study Inhibitor/Concentration Reference
  Caffeine CGK733 KU55933  
Hickson et al., 2004 - - 0.03- 10 μM [6]
Cowell et al., 2005 - - 1-20 μM [7]
Byrant and Helleday, 2006 - - 2-20 μM [21]
Nakai-Murakami et al., 2007 - - 1 mM [32]
Al-Minawi et al., 2008 2 mM 10 μM - [33]
Yamauchi et al., 2008 - - 10 μM [34]
Cruet-Hennequart et al., 2008 - 10 μM 10 μM [10]
Goldstein et al., 2008 - 0.6 μM - [11]
Crescenzi et al., 2008 1-5 mM 10- 20 μM 20- 40 μM [13]
Bhattacharya et al., 2008 - 20 μM - [9]
  1. Selected studies involving the exposure of mammalian cell lines to the ATM and/or ATR inhibitors caffeine, CGK733 and KU55933.