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Table 1 Results of the probit regression analysis comparing combined treatment (lexatumumab (= lexa, 0.75 mg/kg) and irradiation (= RT, 5 × 3 Gy and graded top up doses 0-44.2 Gy) with irradiation alone

From: Combined treatment with lexatumumab and irradiation leads to strongly increased long term tumour control under normoxic and hypoxic conditions

 

const. B0#

RT-dose (B1)

lexa (B2)

normoxia

   

Parameter (MLE*)

- 1.729

0.028

2.062

SE §

0.386

0.012

0.343

p-value

0.0002

0.0294

<0.0001

clamped hypoxia

   

Parameter (MLE)

- 2.424

0.035

2.097

SE

0.489

0.013

0.396

p-value

<0.0001

0.0147

<0.0001

  1. # Regression constant B0
  2. * Maximum likelihood estimate
  3. § Standard error