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Table 2 Volumes by CT and PET-CT in 13 Patients with Malignant Pleural Mesothelioma.

From: Comparison of CT and integrated PET-CT based radiation therapy planning in patients with malignant pleural mesothelioma

Volume, cc

CT

PET-CT

P Value

GTV

   

Mean ± S.D.

788.9 ± 845.1

441.4 ± 420.0

0.01

Min-max

(101.4 - 3352.1)

(38.5 - 1250.2)

 

CTV

   

Mean ± S.D.

2040.6 ± 1360.5

1533.1 ± 1483.6

0.002

Min-max

(479.6 - 5615.8)

(254.4 - 5615.82)

 

PTV1

   

Mean ± S.D.

3824.7 ± 1777.7

2936.7 ± 1940.1

0.003

Min-max

(1062.5 - 7523.8)

(608.9 - 6971.9)

 

PTV2

   

Mean ± S.D.

2385.5 ± 1449.9

1627.9 ± 1254.2

0.003

Min-max

(488.2 - 5853.1)

(278.9 - 4088.4)

 
  1. *Abbreviations: CT = computed tomography; CTV = clinical target volume; GTV = gross tumor volume; PET-CT = positron emission tomography-computed tomography; PTV1 = planning target volume 1 (defined as CTV plus a 1-cm margin); PTV2 = planning target volume 2 (defined as GTV plus a 1-cm margin).