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Table 4 Dosimetric results for OARs and non target tissues

From: RapidArc, intensity modulated photon and proton techniques for recurrent prostate cancer in previously irradiated patients: a treatment planning comparison study

Parameter

IMRT

IMPT

RA_HD120

RA_M120

p

Rectum. Volume [cm3] 48.6 ± 17.6 [28.4-72.5]

D50 [Gy]

10.1 ± 6.2

4.1 ± 4.0

8.2 ± 3.9

9.1 ± 4.2

a,b,d,e,f

D1 [Gy]

49.6 ± 6.8

45.1 ± 9.2

45.2 ± 8.3

46.5 ± 7.8

a,b,c

V35 Gy [%]

9.8 ± 5.3

3.9 ± 2.7

5.1 ± 3.0

5.9 ± 3.3

a,b,c,e

V45 Gy [%]

3.6 ± 2.4

1.6 ± 1.3

1.6 ± 1.1

1.9 ± 1.3

a,b,c

Urethra. Volume [cm3] 0.7 ± 0.1 [0.6-0.8]

D50 [Gy]

31.4 ± 13.1

26.8 ± 11.7

28.6 ± 11.4

28.6 ± 10.9

a,b,c,d,e

D1 [Gy]

40.1 ± 3.3

38.1 ± 2.4

39.8 ± 3.5

39.3 ± 3.3

a,c,d,f

V35 Gy [%]

60.7 ± 41.7

25.1 ± 21.1

38.0 ± 25.3

36.0 ± 24.0

a,b,c

V40 Gy [%]

11.0 ± 12.8

0.6 ± 1.1

5.1 ± 5.4

4.0 ± 5.6

 

Left femoral head Volume [cm3] 60.1 ± 4.4 [54.8-67.6]

D50 [Gy]

3.9 ± 2.6

0.1 ± 0.1

3.3 ± 2.1

3.5 ± 2.1

a,b,d,e,f

D1Gy]

14.6 ± 7.2

2.3 ± 2.0

7.4 ± 1.5

7.6 ± 1.3

a,b,c,d,e

Right femoral head Volume [cm3] 60.9 ± 5.8 [54.6-71.6]

D50 [Gy]

3.9 ± 2.7

0.1 ± 0.1

3.2 ± 2.3

3.4 ± 2.1

a,d,e

D1Gy]

15.3 ± 7.5

2.5 ± 3.0

8.0 ± 1.8

8.0 ± 1.7

a,b,c,d,e

Bladder. Volume [cm3] 109.8 ± 63.6 [32.7-234.2]

D50 [Gy]

4.9 ± 3.2

0.7 ± 0.9

4.6 ± 2.6

5.2 ± 3.0

a,d,e,f

D1 [Gy]

42.3 ± 17.0

38.8 ± 19.6

41.3 ± 16.3

42.1 ± 15.8

 

V35 Gy [%]

6.4 ± 6.3

3.9 ± 4.3

4.1 ± 4.1

4.5 ± 4.2

a

V50 Gy [%]

1.9 ± 2.7

1.4 ± 2.1

1.3 ± 2.1

1.3 ± 2.1

 

Penile bulb. Volume [cm3] 7.2 ± 3.2 [3.0-13.2]

D50 [Gy]

2.0 ± 1.5

0.9 ± 1.4

2.5 ± 1.7

3.2 ± 2.5

a,b,c,d,e

D1 [Gy]

7.6 ± 9.4

7.1 ± 9.0

5.8 ± 4.6

7.7 ± 7.4

 

Non Target Tissue

Mean [Gy]

2.0 ± 0.8

0.7 ± 0.3

1.8 ± 0.7

1.9 ± 0.7

a,b,d,e,f

V10 Gy [%]

6.0 ± 2.6

2.8 ± 1.3

4.7 ± 2.5

5.1 ± 2.8

a,b,c,d,e

CI90

1.3 ± 0.1

1.6 ± 0.2

1.3 ± 0.1

1.3 ± 0.1

a,d,e

DoseInt [Gy*cm3 104]

3.3 ± 1.6

1.1 ± 0.5

2.9 ± 1.3

3.1 ± 1.4

a,b,d,e,f

  1. a = IMRT vs IMPT b = IMRT vs RA_HD120 c = IMRT vs RA_M120
  2. d = IMPT vs RA_HD120 e = IMPT vs RA_M120 f = RA_HD120 vs RA_M120