From: Severe hypoxia induces chemo-resistance in clinical cervical tumors through MVP over-expression
Characteristics | All patients (n = 43) | MVP low (n = 23) | MVP high (n = 20) | P value |
---|---|---|---|---|
Age | 49.48 ± 12.79 | 49.47 ± 13.68 | 49.50 ± 12.04 | |
(29–81) | (29–81) | (32–72) | 0.325 | |
Stage | ||||
I | 14 | 5 | 9 | |
II | 22 | 13 | 9 | |
III | 7 | 5 | 2 | 0.228 |
Histology | ||||
Epidermoid | 38 | 23 | 15 | |
Adenocarcinoma | 5 | 0 | 5 | 0.011 |
Grade | ||||
I | 5 | 3 | 2 | |
II | 19 | 10 | 9 | |
III | 19 | 10 | 9 | 0.952 |
p53 | 39.15 ± 27.62 | 37.53 ± 28.04 | 41.02 ± 27.74 | |
(0–92) | (0–92) | (0–81) | 0.685 | |
Vascular density | 49.62 ± 33.98 | 35.89 ± 22.55 | 65.41 ± 38.38 | |
(0–160) | (0–113) | (12–160) | 0.003 | |
Hypoxic fraction | 35.89 ± 26.80 | 27.26 ± 22.96 | 45.82 ± 28.00 | |
(0–91.30) | (0–66.30) | (0–91.30) | 0.022 | |
Median pO2 | 7.61 ± 8.98 | 7.84 ± 7.85 | 7.36 ± 10.34 | |
(0–41.90) | (0–24.30) | (0–41.90) | 0.863 |