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Table 2 Summary of DVH based analysis for OARs and healthy tissue

From: Simultaneous integrated boost radiotherapy for bilateral breast: a treatment planning and dosimetric comparison for volumetric modulated arc and fixed field intensity modulated therapy

 

Left Lung

Right Lung

 

RapidArc

IMRT

p

RapidArc

IMRT

p

Mean (Gy)

8.7 ± 1.0

7.8 ± 0.9

0.15

9.4 ± 1.2

9.1 ± 1.4

0.4

D 2% (Gy)

34.3 ± 2.3

39.4 ± 4.1

0.04

37.9 ± 1.7

44.8 ± 2.5

0.004

V 5 Gy (%)

58.7 ± 18.9

35.3 ± 3.9

0.004

58.3 ± 18.9

44.4. ± 7.8

0.004

V 20 Gy (%)

9.7 ± 1.3

12.8 ± 2.5

0.04

10.3 ± 1.4

14.5 ± 4.0

0.004

V 45 Gy (%)

0.1 ± 0.2

0.9 ± 0.7

0.04

0.1 ± 0.1

0.9 ± 0.5

0.004

NTCP (%)

<0.1

<0.1

0.3

<0.1

<0.1

0.2

 

Heart

   
 

RapidArc

IMRT

p

   

Mean (Gy)

6.0 ± 2.7

7.4 ± 2.5

0.14

   

D 2% (Gy)

17.0 ± 6.6

24.4 ± 7.1

0.04

   

V 10 Gy (%)

13.1 ± 14.1

19.5 ± 13.3

0.04

   

V 45 Gy (%)

0.0 ± 0.0

0.1 ± 0.1

0.12

   

NTCP (%)

<0.1

<0.1

0.25

   
 

Healthy Tissue

   
 

RapidArc

IMRT

p

   

Mean (Gy)

7.1 ± 0.3

5.0 ± 0.4

0.03

   

V 3 Gy (%)

50.1 ± 8.7

33.5 ± 6.1

0.03

   

V 10 Gy (%)

20.5 ± 3.3

18.3 ± 2.7

0.19

   

CI 90

1.19 ± 0.07

1.20 ± 0.07

0.19

   

CI 95

1.10 ± 0.06

1.14 ± 0.09

0.19

   

EI (%)

3.7 ± 1.9

8.7 ± 2.9

0.19

   

DoseInt (Gycm -3 10 5 )

1.40 ± 0.36

1.15 ± 0.27

0.03

   
  1. Data are reported as mean ± 1 standard deviation computed over the cohort of 10 patients.
  2. Dx% = dose received by the x% of the volume; VxGy = volume receiving at least × Gy; CI = ratio between the patient volume receiving at least 90% and 95% of the prescribed dose and the volume of the total PTVII; EI = VD/VPTVII where VPTVII is the volume of the total PTVII and VD is the volume of healthy tissue receiving more than 50 Gy; DoseInt = integral of the absorbed dose extended to over all voxels excluding those within the target volume; NTCP = Normal Tissue Control Probability with the relative seriality model.
  3. * p < 0.05; ** p < 0.01