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Table 2 Summary of DVH based analysis for OARs and healthy tissue

From: Simultaneous integrated boost radiotherapy for bilateral breast: a treatment planning and dosimetric comparison for volumetric modulated arc and fixed field intensity modulated therapy

  Left Lung Right Lung
  RapidArc IMRT p RapidArc IMRT p
Mean (Gy) 8.7 ± 1.0 7.8 ± 0.9 0.15 9.4 ± 1.2 9.1 ± 1.4 0.4
D 2% (Gy) 34.3 ± 2.3 39.4 ± 4.1 0.04 37.9 ± 1.7 44.8 ± 2.5 0.004
V 5 Gy (%) 58.7 ± 18.9 35.3 ± 3.9 0.004 58.3 ± 18.9 44.4. ± 7.8 0.004
V 20 Gy (%) 9.7 ± 1.3 12.8 ± 2.5 0.04 10.3 ± 1.4 14.5 ± 4.0 0.004
V 45 Gy (%) 0.1 ± 0.2 0.9 ± 0.7 0.04 0.1 ± 0.1 0.9 ± 0.5 0.004
NTCP (%) <0.1 <0.1 0.3 <0.1 <0.1 0.2
  Heart    
  RapidArc IMRT p    
Mean (Gy) 6.0 ± 2.7 7.4 ± 2.5 0.14    
D 2% (Gy) 17.0 ± 6.6 24.4 ± 7.1 0.04    
V 10 Gy (%) 13.1 ± 14.1 19.5 ± 13.3 0.04    
V 45 Gy (%) 0.0 ± 0.0 0.1 ± 0.1 0.12    
NTCP (%) <0.1 <0.1 0.25    
  Healthy Tissue    
  RapidArc IMRT p    
Mean (Gy) 7.1 ± 0.3 5.0 ± 0.4 0.03    
V 3 Gy (%) 50.1 ± 8.7 33.5 ± 6.1 0.03    
V 10 Gy (%) 20.5 ± 3.3 18.3 ± 2.7 0.19    
CI 90 1.19 ± 0.07 1.20 ± 0.07 0.19    
CI 95 1.10 ± 0.06 1.14 ± 0.09 0.19    
EI (%) 3.7 ± 1.9 8.7 ± 2.9 0.19    
DoseInt (Gycm -3 10 5 ) 1.40 ± 0.36 1.15 ± 0.27 0.03    
  1. Data are reported as mean ± 1 standard deviation computed over the cohort of 10 patients.
  2. Dx% = dose received by the x% of the volume; VxGy = volume receiving at least × Gy; CI = ratio between the patient volume receiving at least 90% and 95% of the prescribed dose and the volume of the total PTVII; EI = VD/VPTVII where VPTVII is the volume of the total PTVII and VD is the volume of healthy tissue receiving more than 50 Gy; DoseInt = integral of the absorbed dose extended to over all voxels excluding those within the target volume; NTCP = Normal Tissue Control Probability with the relative seriality model.
  3. * p < 0.05; ** p < 0.01