Weak expression of cyclooxygenase-2 is associated with poorer outcome in endemic nasopharyngeal carcinoma: analysis of data from randomized trial between radiation alone versus concurrent chemo-radiation (SQNP-01)

Table 1 Patients' characteristics

Characteristic	Patients with COX-2 IHC No. (%) (N = 58)	Patients without COX-2 IHC No. (%) (N = 163)	P
Age (years)
Median (Range)	44 (30–74)	46 (14–76)	0.594
Sex
Male	49 (84.5%)	131 (80.4%)
Female	9 (15.5%)	32 (19.6%)	0.559
T status
1	9 (15.5%)	19 (11.7%)
2	13 (22.4%)	52 (31.9%)
3	17 (29.3%)	48 (29.5%)
4	19 (32.8%)	44 (27.0%)	0.497
N status
0	4 (6.9%)	19 (11.7%)
1	10 (17.2%)	18 (11.0%)
2	23 (39.7%)	85 (52.2%)
3	21 (36.2%)	41 (25.2%)	0.143
TNM stage
II	-	1 (0.6%)
III	25 (43.1%)	80 (49.1%)
IV	33 (56.9%)	82 (50.3%)	0.592
Treatment
RT	27 (46.6%)	83 (50.9%)
CRT	31 (53.4%)	80 (49.1%)	0.647

Abbreviations: COX-2, cyclooxygenase-2; IHC, immunohistochemistry; RT, radiation; CRT, chemo-radiation.

ISSN: 1748-717X