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Table 4 Analysis of demographic, clinical, histological, molecular and therapeutic characteristics of patients treated with mastectomy and breast conservative therapy (BCT) (test Pearson Khi2)

From: Concurrent chemoradiotherapy in adjuvant treatment of breast cancer

Patients characteristics

Mastectomy [n = 205] No (%)

BCT [n = 39] No (%)

p value

Age

   <40

48 (23.4%)

6 (15.4%)

0.268

   ≥40

157 (76.6%)

33 (84.6%)

 

Menopausal status

   No

129 (67.5%)

23 (63.9%)

0.669

   Yes

62 (32.5%)

13 (36.1%)

 

Side

   Right

48 (43.6%)

71 (53%)

0.146

   Left

62 (56.4%)

63 (47%)

 

Histology

   DIC

183 (91.1%)

36 (100%)

0.062

   LIC

18 (9%)

0

 

SBR

   I

13 (6.6%)

4 (10.5%)

0.53

   II

130 (65.7%)

26 (68.4%)

 

   III

55 (27.8%)

8 (21.1%)

 

Hormone receptors

ER

   Positive

120 (60.3%)

28 (71.8%)

0.877

   Negative

79 (39.7%)

11 (28.2%)

 

PR

   Positive

61 (57.5%)

23 (59%)

0.877

   Negative

45 (42.5%)

16 (41%)

 

Tumour

   pT1

25 (12.4%)

10 (25.6%)

0.003

   pT2

111 (55.2%)

27 (69.2%)

 

   pT3

55 (27.4%)

2 (5.1%)

 

   pT4

10 (5%)

0

 

pN, axillary

   pN0

49 (23.9%)

11 (28.2%)

0.285

   pN1

57 (27.8%)

15 (38.5%)

 

   pN2

63 (30.7%)

10 (25.6%)

 

   pN3

36 (17.6%)

3 (7.7%)

 

Protocol

   Anthracycline

89 (43.4%)

21 (53.8%)

0.23

   CMF

116 (56.6%)

18 (46.2%)

 

Breast/thoracic wall irradiation

   Yes

194 (94.6%)

39 (100%)

0.139

   No

11 (5.4%)

0

 

Prophylactic supraclavicular fossa radiotherapy

   Yes

193 (94.1%)

38 (97.4%)

0.402

   No

12 (5.9%)

1 (2.6%)

 

Internal mammary radiotherapy

   Yes

195 (94.1%)

38 (97.4%)

0.523

   No

10 (5.9%)

1 (2.6%)

 

Axillary radiotherapy

   Yes

42 (20.5%)

7 (17.9%)

0.717

   No

163 (79.5%)

32 (82.1%)

 
  1. SBR = Scarf-Bloom-Richardson; DIC = ductal invasive carcinoma; LIC = lobular invasive carcinoma; ER = estrogen receptor; PR = progesterone receptor