| Cumulative dose plan CT-based | Cumulative dose plan Conventional | p-values |
---|---|---|---|
Target coverage (%) | Â | Â | Â |
   Breast PTVCT ≥ 95% | 99.2 (97.7 – 100.0) | 95.3 (84.5 – 100.0) | < 0.001 |
   Boost PTVCT ≥ 95% | 99.6 (98.0 – 100.0) | 90.1 (70.3 – 100.0) | < 0.001 |
Irradiated volumes (cm3) | Â | Â | Â |
   Volume ≥ 95% * 50 Gy | 1276 (461 – 2239) | 1142 (518 – 1968) | 0.01 |
   Volume ≥ 95% * 66 Gy | 241 (105 – 491) | 187 (84 – 376) | < 0.001 |
Excess volumes (cm3) | Â | Â | Â |
   ≥ 95% * 50 Gy outside breast PTVCT | 529 (257–1114) | 427 (143 – 857) | 0.02 |
   ≥ 95% * 66 Gy outside boost PTVCT | 124 (65 – 260) | 82 (31 – 144) | < 0.001 |