Skip to main content

Table 1 A comparison of doses to the heart and ipsilateral lung dosimetry from the MammoSite catheter and external beam radiotherapy using the standard dosimetric parameters.

From: Dose volume histogram analysis of normal structures associated with accelerated partial breast irradiation delivered by high dose rate brachytherapy and comparison with whole breast external beam radiotherapy fields

Dosimetric Parameters

MammoSite (34 Gy/10#/1 week)

External Beam (50 Gy/25#/5 weeks)

p-value

 

Mean

Range

Mean

Range

 

Lung n = 5

     

Dmean

4.2 Gy

2.1–5.6 Gy

6.5 Gy

2.6–11.8 Gy

p = 0.18

Dmax

31 Gy

6.3–45.7 Gy

51.6 Gy

49.7–55.9 Gy

p = 0.06

V30 (cc)

2 cc

0–7.2 cc

86.7 cc

31.5–184 cc

p = 0.04*

V30 (%)

0.2%

0–0.5%

8.3%

2.3–19.9%

p = 0.04*

V20 (cc)

13.4 cc

0–34.6 cc

105 cc

46.1–205 cc

p = 0.04*

V20 (%)

1.3%

0–2.5%

10%

3.3–22.2%

p = 0.04*

V10 (cc)

83.3 cc

0–170 cc

133.6 cc

67.8–235 cc

p = 0.31

V10 (%)

8%

0–13.3%

12.8%

4.9–25.4%

p = 0.20

D5

11.3 Gy

3.9–15.3 Gy

49.9 Gy

47.5–53.4 Gy

p = 0.005*

Heart

     

Dmean

3.8 Gy

3.1–4.8 Gy

3.5 Gy

1.1 – 5.1 Gy

p = 0.63

Dmax

16.6 Gy

10.6–27.2 Gy

44.1 Gy

15.5–51.8 Gy

p = 0.004*

V20 (cc)

0.3 cc

0–1.5 cc

15.6 cc

0–23.9 cc

p = 0.008*

V20 (%)

0.1%

0–0.3%

3.7%

0–5.3%

p = 0.001*

V10 (cc)

10.6 cc

0.2–33.6 cc

22.9 cc

0.3–39.0 cc

p = 0.07

V10 (%)

2.5%

0–7.5%

5.4%

0.1–8.7%

p = 0.07

V5 (cc)

83.8 cc

46.9–145.0 cc

41.5 cc

3.1–82.3 cc

p = 0.006*

V5 (%)

19.8%

11.0–32.2%

9.6%

0.8–18.3%

p = 0.008*

D20

8.5 Gy

6.4–11.9 Gy

15.3 Gy

2.3–24.3 Gy

p = 0.10

D30

7.5 Gy

5.8–10.4 Gy

7.6 Gy

2–14.0 Gy

p = 0.94

  1. * represents a statistically significant p-value