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Table 1 A comparison of doses to the heart and ipsilateral lung dosimetry from the MammoSite catheter and external beam radiotherapy using the standard dosimetric parameters.

From: Dose volume histogram analysis of normal structures associated with accelerated partial breast irradiation delivered by high dose rate brachytherapy and comparison with whole breast external beam radiotherapy fields

Dosimetric Parameters MammoSite (34 Gy/10#/1 week) External Beam (50 Gy/25#/5 weeks) p-value
  Mean Range Mean Range  
Lung n = 5      
Dmean 4.2 Gy 2.1–5.6 Gy 6.5 Gy 2.6–11.8 Gy p = 0.18
Dmax 31 Gy 6.3–45.7 Gy 51.6 Gy 49.7–55.9 Gy p = 0.06
V30 (cc) 2 cc 0–7.2 cc 86.7 cc 31.5–184 cc p = 0.04*
V30 (%) 0.2% 0–0.5% 8.3% 2.3–19.9% p = 0.04*
V20 (cc) 13.4 cc 0–34.6 cc 105 cc 46.1–205 cc p = 0.04*
V20 (%) 1.3% 0–2.5% 10% 3.3–22.2% p = 0.04*
V10 (cc) 83.3 cc 0–170 cc 133.6 cc 67.8–235 cc p = 0.31
V10 (%) 8% 0–13.3% 12.8% 4.9–25.4% p = 0.20
D5 11.3 Gy 3.9–15.3 Gy 49.9 Gy 47.5–53.4 Gy p = 0.005*
Heart      
Dmean 3.8 Gy 3.1–4.8 Gy 3.5 Gy 1.1 – 5.1 Gy p = 0.63
Dmax 16.6 Gy 10.6–27.2 Gy 44.1 Gy 15.5–51.8 Gy p = 0.004*
V20 (cc) 0.3 cc 0–1.5 cc 15.6 cc 0–23.9 cc p = 0.008*
V20 (%) 0.1% 0–0.3% 3.7% 0–5.3% p = 0.001*
V10 (cc) 10.6 cc 0.2–33.6 cc 22.9 cc 0.3–39.0 cc p = 0.07
V10 (%) 2.5% 0–7.5% 5.4% 0.1–8.7% p = 0.07
V5 (cc) 83.8 cc 46.9–145.0 cc 41.5 cc 3.1–82.3 cc p = 0.006*
V5 (%) 19.8% 11.0–32.2% 9.6% 0.8–18.3% p = 0.008*
D20 8.5 Gy 6.4–11.9 Gy 15.3 Gy 2.3–24.3 Gy p = 0.10
D30 7.5 Gy 5.8–10.4 Gy 7.6 Gy 2–14.0 Gy p = 0.94
  1. * represents a statistically significant p-value