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Table 6 Comparison of acute and late GI and GU toxicity rates with the literature

From: Acute and late toxicity in prostate cancer patients treated by dose escalated intensity modulated radiation therapy and organ tracking

Study Pts RT Dose (Gy) FU (months) Tox Acute GI grade 2/3 Late GI grade 2/3 Acute GU grade 2/3 Late GU grade 2/3 Ref
Skala et al. 690 3D/IMRT ≤ 79.8 37# RTOG n.a. 2.5%/0.7% n.a. 8.8/0.9 22
Lips et al. 331 IMRT 76 47* CTC/RTOG1 30%/0 9%/1% 47%/3%2 21%/4%2 23
Current study 39 IMRT 80 29# CTC 3%/0 8%/0 61%/3% 26%/3%  
  1. Abbreviations: GI = gastrointestinal; GU = genitourinary; Pts = patients; RT = radiotherapy; FU = follow-up; Tox = toxicity score used; Ref = reference; 3D = three-dimensional conformal radiation therapy; IMRT = intensity modulated radiation therapy; RTOG = Radiation Therapy Oncology Group toxicity criteria; n.a. = not applicable; CTC = Common Toxicity Criteria; # median (months); * mean (months); 1 For acute toxicity CTC criteria were used and for late toxicity RTOG criteria. 2 plus 0.3% of patients with grade 4 toxicity.
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