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Figure 1 | Radiation Oncology

Figure 1

From: A phase I radiation dose-escalation study to determine the maximal dose of radiotherapy in combination with weekly gemcitabine in patients with locally advanced pancreatic adenocarcinoma

Figure 1

Treatment scheme: different RT dose levels to be investigated. Radiotherapy dose escalation scheme investigated in this phase I trial; gemcitabine (G) was administered on day 1 of week 1, 2, 3, 4 and 5 in a single dose of 300 mg/m2 as a 30-min IV infusion at least one hour prior to RT; the starting dose of RT was 45 Gy in 25 fractions of 1.8 Gy per day (XRT); dose escalation was achieved by giving 2 fractions of 1.8 Gy per day on a fixed day, with an interfraction interval of at least 6 hours, an arrow indicates an extra fraction of 1.8 Gy on that day; the escalating dose levels tested were: 54 Gy, 59.4 Gy and 63 Gy; the total duration of the RT was kept on 5 weeks.

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Radiation Oncology

ISSN: 1748-717X

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