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Table 2 Recurrent breast cancer treated with reirradiation.

From: Reirradiation of recurrent breast cancer with and without concurrent chemotherapy

Pat.

Initial dose Gy

Reirrad. Dose (Gy)

Dose 1 +2 Gy

BED3 Gy

Interval (m)

Overlapping treatment volume

Chemo-therapy

Surgery for recurrence

2

55

50,4

105,4

178,1

133,6

Subpectoral + infraclavicular

5-FU

Segmental resection (BCT)

6

60,4

56

116,4

182,5

20,4

Left thoracic wall

none

mastectomy, ax. diss.

7

60

51,2

101,2

188,5

220,5

Caudal thoracic wall

5-FU

Local excision

9

45

54,4

99,4

155,4

26,8

Cranial thoracic wall

none

mastectomy, LN

15

60

51,2

111,2

198,5

161,5

Mastectomy scar

none

Thoracic wall resection,

18

50

57,6

107,6

175,5

8,7

lateral thoracic wall, ax.

none

Local excision

19

60,4

61,2

121,6

194,6

42,8

upper outer quadrant, ax.

Taxotere

resection, ax. diss. (BCT)

23

60

50,4

110,4

180,6

135,1

Left thoracic wall

none

reconstructive surgery

24

60,4

55,8

116,2

185,9

42,5

Mastectomy scar

Capecitab.

None

25

60

50,4

110,4

180,6

212,6

Left lower quadrant

none

Local excision (BCT)

26

50

50,4

100,4

172,3

290,1

Left thoracic wall

none

Thoracic wall resection

27

50

46

96

160,0

114

Right lower inner quadrant

none

Mastectomy post- reirradiation

28

60

59,4

119,4

195,0

175,0

Right upper quadrant

none

wide excision (BCT)

1

50

50,4

100,4

164,0

184,7

Lateral thoracic wall

none

none

3

50,4

30

80,4

130,6

32,5

Thoracic wall

Capecitab.

None

4

60

45

105

172,0

23,5

Thoracic wall

Capecitab.

None

5

64

44,8

108,8

175,4

52,6

Whole thoracic wall

Capecitab.

None

8

60,4

50

110,4

180,0

85,9

parasternal

none

None

10

50,4

57,6

108

169,0

50,2

Thoracic wall

5-FU

None

11

66,6

59,4

126

201,6

69,5

Lat.thoracic wall

none

None

12

50,4

45

95,4

152,6

8,7

Thoracic wall, lateral

none

None

13

60,0

50,4

110,4

180,6

49,9

Upper quadrants

none

None

14

60,4

50,4

110,8

177,3

28,7

Upper outer quadrant

5-FU

none

16

55

49

104

186,6

185,2

parasternal

none

None

17

42,5

45

87,5

149,9

201,2

supraclav., apex ax.

none

None

20

50

48

98

163,3

32,7

Sternal + infraclav.

Capecitab.

None

21

59,4

44

103,4

168,4

53,1

Thoracic wall

none

None

22

59,4

46

105,4

177,7

20,0

Thoracic wall

none

None

29

50,4

50

100,4

164,0

31,1

Thoracic wall

none

None

  1. Pat.: patient number ; BCT: breast conserving therapy for recurrence; LN: lymph nodes; ax. diss: axillary dissection; capecitab.: capecitabine.
  2. Treatment details of recurrent breast carcinoma patients treated with reirradiation. Radiation doses (Gy) of initial radiotherapy and reirradiation, the cumulative dose (dose 1 + 2) and the cumulative BED3 Gy (Gy) are shown. For the initial treatment, whole breast plus boost dose is given, if retreatment volume included the initial boost volume. The interval between the last day of the initial radiotherapy and first day of reirradiation is given in months.