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Figure 6 | Radiation Oncology

Figure 6

From: In vitro studies on the modification of low-dose hyper-radiosensitivity in prostate cancer cells by incubation with genistein and estradiol

Figure 6

Western-Blot analysis of p21 and actin in LNCaP after 24 h of hormonal incubation, irradiation with 0.5 Gy and 4 Gy. 6 h after irradiation the cells were harvested and subjected to protein extraction. The shown results represent one of three assays. In controls incubated in FCS containing media and in controls incubated in media with FCS-withdrawal there was a induction of p21 expression. The same was seen in cells after incubation with low doses of estradiol (0.01 μM) and genistein (0.01 μM). After incubation with high concentrations of estradiol (10 μM) and genistein (10 μM) the induction of p21 was completely abolished.

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