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Figure 2 | Radiation Oncology

Figure 2

From: In vitro studies on the modification of low-dose hyper-radiosensitivity in prostate cancer cells by incubation with genistein and estradiol

Figure 2

Clonogenic survival LNCaP (left side) and PC-3 (right side) after incubation with genistein (LNCaP 48 h incubation, PC-3 24 h). Survival was expressed relative to untreated controls. Error bars represent standard errors. In both cell lines a significant reduction in colony forming is observed after incubation with genistein. Colony formation was reduced to 50% of the controls in LNCaP afer incubation with genistein 0.01 μM (p = 0.004). Higher genistein concentrations (0.1 μM and 10 μM) did not further suppress clonogenic survival. In PC-3 incubation with genistein 0.1 μM decreased colony formation to 75% of the controls (p = 0.027), higher concentrations reduced clonogenic survival further (10 μM: p < 0.001; 25 μM: p < 0.001).

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Radiation Oncology

ISSN: 1748-717X

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