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Table 4 Average normal tissue dose-volume parameters based on PTVpre and PTVreal in each original and simulated IMRT plans

From: Conventionally-fractionated image-guided intensity modulated radiotherapy (IG-IMRT): a safe and effective treatment for cancer spinal metastasis

Normal tissue parameter

Average parameters based on PTVpre

Average parameters based on PTVreal

Average parameters reductions from PTVpre to PTVreal (%)

Lung (n = 4)

   

   Maximum dose

57.3 Gy

55.2 Gy

3.7

   Average dose

10.8 Gy

9.2 Gy

14.8

   V20

12.2%

10.9%

10.7

   V12.5

23.5%

20.1%

14.5

Liver (n = 4)

   

   Maximum dose

58.6 Gy

56.1 Gy

4.3

   Average dose

14.6 Gy

11.7 Gy

19.9

   V30

12%

8%

33.3

   V20

27%

19%

29.6

   V10

38%

30%

21.1

kidney (n = 4)

   

   Maximum dose

60.2 Gy

57.8 Gy

4.0

   Average dose

14.6 Gy

11.4 Gy

21.9

   V30

7%

4%

42.9

   V20

21%

16%

23.8

   V10

39%

31%

20.5

Cord (n = 10)

   

   Maximum dose

68.4 Gy

49.1 Gy

28.2

   Average dose

34.3 Gy

31.2 Gy

9.1

   D5spine

54.4 Gy

45.3 Gy

16.7

  1. PTVpre: simulated PTV based on the theoretic margins in the three axes without online set-up correction; PTVreal: actual PTV in the original IMRT plans; D5spine: maximum dose in 5% volume of the spinal cord.