Comparing two strategies of dynamic intensity modulated radiation therapy (dIMRT) with 3-dimensional conformal radiation therapy (3DCRT) in the hypofractionated treatment of high-risk prostate cancer

Table 1 Tumor and Normal Tissue Initial Tomotherapy Plan Optimization Parameters

Tumor Constraints
Conformal Pelvic Vessel Targeting
Structure	Importance	Max Dose (Gy)	Max Dose Penalty	DVH Volume (%)	DVH Dose (Gy)	Minimum Dose (Gy)	Minimum Dose Penalty
PTV1	10	68	10	95	68	68	33
Rt Iliac Nodal Volume	10	68	1	95	45	45	10
Lt Iliac Nodal Volume	10	68	1	95	45	45	10
PTV1 = prostate + 7.5 mm
Conformal Normal Tissue Avoidance
Structure	Importance	Max Dose (Gy)	Max Dose Penalty	DVH Volume (%)	DVH Dose (Gy)	Minimum Dose (Gy)	Minimum Dose Penalty
PTV1	10	68	10	95	68	68	33
PTV_cnta	10	68	10	95	45	45	10
PTV_cnta = PTV1 + lymph node planning target volume + pelvic soft tissue target
Sensitive Structure Constraints
Structure	Importance	Max Dose (Gy)	Max Dose Penalty	DVH Volume (%)	DVH Dose (Gy)	DVH Penalty
Rectum	1	68	1	40	30	1
Bladder	1	68	1	40	30	1
Lt Femur	1	45	1	50	20	1
Rt Femur	1	45	1	50	20	1
Small Bowel	1	40	1	1	38	1
Field Width = 5.0 cm Pitch = 0.286 Planning Modulation Factor = 4.0

ISSN: 1748-717X