Salvage radiotherapy for biochemical relapse after complete PSA response following radical prostatectomy: outcome and prognostic factors for patients who have never received hormonal therapy

Table 2 Uni and multivariate analysis

		3-year BNED (%)	Univariate analysis	Multivariate analysis
	Variable		p	p (95% CI)
Gleason Score
	≤7	61	0.25	0.38
	>7	78
Pathological Stage
	≤pT3a	77	0.59	0.63
	pT3a or pT3b	64
Surgical Margins
	compromised	67	0.65	0.5
	clear	74
PNLVSI
	positive	68	0.31	0.29
	negative	100
Time to recurrence after RP
	≤12 meses	75	0.9	0.85
	>12 meses	66
PSADT
	≤4 meses	48.4	0.01	0.01
	>4 meses	75.6
Preradiation PSA
	≤1 ng/ml	75.9	0.1	0.7
	>1 ng/ml	48.1
Time to radiation after recurrence
	≤3 months	100	0.04	0.1
	>3 months	60
Clinical tumor on surgical bed
	Yes	80	0.4	0.46
	No	66
Radiation dose (Gy)
	≤66 Gy	76	0.62	0.7
	>66 Gy	68

CI, confidence interval; PNLVSI, perineural or lymphatic or vascular space invasion; PSADT, PSA doubling time; Gy, Gray.