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Table 2 Comparison of APP cream and aloe vera gel effectiveness during RT.

From: A phase III trial comparing an anionic phospholipid-based cream and aloe vera-based gel in the prevention of radiation dermatitis in pediatric patients

Assessment

Variable*

No difference

Cream > Gel

Gel > Cream

Cream > Gel, Gel > Cream

P-value†

Subject Skin Comfort

Dry

25

2

15

2

0.002

 

Soft

27

11

3

3

0.057

 

Feels good

28

13

1

2

0.002

 

Rough

31

2

9

2

0.065

 

Smooth

32

10

1

1

0.012

Dermatologic

Dryness

25

3

14

2

0.013

 

Erythema

33

0

10

1

0.002

 

Peely

35

0

8

1

0.008

Common Toxicity Criteria

CTC value

34

0

9

1

0.004

  1. *The p-values of all variables listed, except CTC value, were less than 0.05.
  2. †Two-sided exact p-value for equality of cream > gel frequency and gel > cream frequency.