Table 1 Patients' characteristics
| Â | Smoker | Non Smoker | Â |
|---|---|---|---|
n | 34 | 34 | Â |
mean age (range) | 55 (34 – 77) | 62 (38–86) | p = 0.21 |
male:female | 18:16 | 7:27 | p = 0.006 |
Localisation | Â | Â | ns |
   Anal canal | 19 | 27 |  |
   Anal verge | 10 | 2 |  |
   Overlapping | 5 | 5 |  |
T-Stage | Â | Â | ns |
   T1 | 3 | 7 |  |
   T2 | 19 | 19 |  |
   T3 | 10 | 3 |  |
   T4 | 2 | 5 |  |
N-Stage | Â | Â | ns |
   N 0 | 25 | 22 |  |
   N + | 9 | 12 |  |
Therapy Protocol | Â | Â | ns |
   Cummings | 3 | 3 |  |
   EORTC | 1 | 3 |  |
   RTOG | 30 | 28 |  |