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Table 2 Mean scores of the scales and single items of questionnaire for patients with cancer of the head- and-neck treated with radiotherapy with or without surgery. A significant outcome presents a significant change in time towards improvement starting 6 weeks after RT.

From: Quality of life and salivary output in patients with head-and-neck cancer five years after radiotherapy

  pre-RT 6 weeks 6 mo 12 mo 5 years Significance
EORTC QLQ-C30(+3)       
Functioning scales*       
   Cognitive 90.1 88.0 88.6 90.2 87.3 NS
   Emotional 75.8 83.5 83.2 85.5 83.7 NS
   Physical 80.6 85.0 85.0 87.0 85.1 NS
   Role 75.8 83.5 83.2 85.5 83.7 NS
   Social 86.9 88.8 89.4 93.6 87.8 NS
Global QOL* 71.6 73.3 80.1 81.6 80.6 NS
Symptom scales†       
   Fatique 24.3 30.5 26.8 23.4 27.5 p < 0.01
   Pain 14.3 11.6 15.0 8.6 12.0 NS
   Nausea and vomiting 3.6 7.4 1.2 2.2 0.8 p < 0.01
Single items†       
   Dyspnoea 16.7 13.2 18.7 15.4 14.3 NS
   Insomnia 24.6 25.6 21.1 17.0 15.5 p < 0.01
   Appetite loss 7.9 14.0 8.9 7.7 10.1 p < 0.05
   Constipation 3.2 10.1 5.7 7.7 7.0 NS
   Diarrhoea 1.6 2.3 1.6 6.0 0.0 NS
   Financial problems 5.6 5.4 4.1 5.1 5.7 NS
EORTC QLQ-H&N35       
Symptom scales-single items†       
   Pain 10.6 19.4 19.1 15.5 9.5 p < 0.01
   Swallowing 9.8 20.5 18.2 11.4 9.9 p < 0.01
   Senses (taste/smell) 5.6 23.3 17.1 12.0 12.3 p < 0.01
   Speech 23.8 17.8 15.0 11.5 14.4 p < 0.01
   Social eating 7.9 19.8 14.8 10.7 10.6 p < 0.01
   Social contact 4.0 6.2 2.6 3.8 4.6 NS
   Sexuality 14.8 78.7 17.1 20.7 25.4 NS
   Teeth 10.5 31.8 21.1 19.8 18.7 NS
   Open mouth (trismus) 11.1 14.0 15.5 9.4 13.9 NS
   Dry mouth 11.9 48.8 50.4 47.0 41.1 p = 0.01
   Sticky saliva 14.6 46.5 40.7 35.0 24.6 p < 0.01
   Cough 17.5 23.3 26.0 18.8 13.5 p < 0.01
   Nutrition supplements 7.3 32.6 12.2 12.8 4.9 p < 0.01
  1. *Higher score indicates better function. † Higher score indicates more symptoms. ‡ Significance based on ordinal regression model using non-transformed data. QLQ, quality of life; RT, radiotherapy; NS, not significant.