Figure 5
ITV optimization. The effect of optimization to an ITV incorporating 4DCT information. Reference 4DCT phase at end-exhalation (a) and end-inhalation (b) with GTV and ITV contours in white. c) If treatment plan optimization to the ITV is based on the reference 4DCT phase only, dose coverage of GTVinhale can not be guaranteed. d) GTVinhale coverage is achieved by including range information of all 4DCT phases into the optimization of the ITV based treatment plan. The dose distributions in c) and d) are calculated for a stationary target and end-inhalation.