Factor | Univariate | Multivariate* | ||||
---|---|---|---|---|---|---|
HR | (95% CI) | p-value | HR | (95% CI) | p-value | |
Radiation therapy | 0.19 | (0.11–0.31) | < 0.001 | 0.21* | (0.13 – 0.34) | < 0.001 |
Radiotherapy dose (>50 Gy) | 0.60 | (0.38–0.97) | 0.028 | |||
Fraction size (≥ 2 Gy) | 0.59 | (0.37–0.95) | 0.036 | |||
Resection margins* | 1.07 | (0.72–1.58) | n.s. | |||
Indication radiotherapy | ||||||
Adjuvant radiotherapy | 0.42 | (0.25–0.72) | 0.002 | |||
Radiotherapy at recurrence | 2.69 | (1.63–4.41) | < 0.001 | |||
Primary radiotherapy | 0.36 | (0.11–1.15) | n. s. | |||
Tumour localization | ||||||
Head-neck | 0.96 | (0.46–2.00) | n.s. | |||
Trunk | 0.67 | (0.37–1.18) | n.s. | |||
Abdominal wall | 0.42 | (0.21–0.85) | 0.017 | 0.28* | (0.15 – 0.53) | < 0.001 |
Extremities* | 2.5 | (1.68–3.62) | < 0.001 | |||
Potential etiological factors | 0.90 | (0.61–1.32) | n.s. | |||
Gender (male) | 0.95 | (0.62–1.45) | n.s. | |||
Age (years) | 0.99 | (0.98–1.00) | n.s. |